Fibrinogen gene variation and ischemic stroke
نویسندگان
چکیده
منابع مشابه
Fibrinogen in Ischemic Stroke
Background and Purpose—To determine the contribution of fibrinogen levels and FGG haplotypes to ischemic stroke. Methods—Associations between fibrinogen levels, fibrinogen /total fibrinogen ratio, and FGG haplotypes with the risk of ischemic stroke were determined in 124 cases and 125 controls. Results—Fibrinogen /total fibrinogen ratio was higher in patients than in controls during the acute p...
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Background and Purpose—PDE4D was identified as the first novel gene associated with ischemic stroke risk. Replication studies have produced conflicting results, but many have been small and underpowered. Meta-analysis provides a method to combine this data and determine in a larger sample size whether the association with PDE4D can be replicated. Methods—A meta-analysis of all PDE4D variants in...
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Introduction: stroke is the most important brain disease. Stroke leads to a reduction in bone density, altered calcium homeostasis, and an increase in hip fractures. Some recent studies show effects of vitamin D on stroke and vice versa. The purpose of this study was to determine of serum vitamin D levels in patients with acute stroke. Methods: In this cross-sectional study, we compared t...
متن کاملIs Plasma Fibrinogen Useful in Evaluating Ischemic Stroke Patients?
See related article, pages 1687–1691. In this issue of Stroke, del Zoppo et al1 report new data on the association between hyperfibrinogenemia and functional prognosis after ischemic stroke using the placebo data from 2 well-known clinical interventional trials on the use of defibrinogenating agent ancrod in acute ischemic stroke.2,3 Briefly, the authors explore the relationship of fibrinogen w...
متن کاملβ-Fibrinogen Gene -455 G/A Polymorphism in Korean Ischemic Stroke Patients
BACKGROUND AND PURPOSE We investigated the relationship between the beta-fibrinogen gene (FGB) -455 G/A polymorphism and plasma fibrinogen levels in Korean ischemic stroke patients. We also determined whether the frequency of the -455 G/A polymorphism differed between two subtypes of noncardioembolic stroke: large-artery atherosclerosis (LAA) and small-vessel occlusion (SVO). METHODS A total ...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2008
ISSN: 1538-7933,1538-7836
DOI: 10.1111/j.1538-7836.2008.02950.x